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Article

The complex relationship between genotype, pathology and phenotype in familial dementia

11 Sept 2020

Abstract excerpt

Causative genes involved in familial forms of dementias, including Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD) and dementia with Lewy bodies (DLB), as well as amyotrophic lateral sclerosis and prion diseases where dementia is present as a significant clinical feature, are associated with distinct proteinopathies. This review summarizes the relationship between known genetic determinants of...

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PMID: 32927063
DOI: 10.1016/j.nbd.2020.105082

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