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Using bioinformatics and metabolomics to identify altered granulosa cells in patients with diminished ovarian reserve

28 Aug 2020

Abstract excerpt

BACKGROUND: During fertility treatment, diminished ovarian reserve (DOR) is a challenge that can seriously affect a patient's reproductive potential. However, the pathogenesis of DOR is still unclear and its treatment options are limited. This study aimed to explore DOR's molecular mechanisms. METHODS: We used R software to analyze the mRNA microarray dataset E-MTAB-391 downloaded from ArrayExpress, screen for...

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Share to Ovarian function and disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32923184
DOI: 10.7717/peerj.9812

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