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Eating the unknown: Xenophagy and ER-phagy are cytoprotective defenses against pathogens

9 Sept 2020

Abstract excerpt

Autophagy is an evolutionary conserved catabolic process devoted to the removal of unnecessary and harmful cellular components. In its general form, autophagy governs cellular lifecycle through the formation of double membrane vesicles, termed autophagosomes, that enwrap and deliver unwanted intracellular components to lysosomes. In addition to this omniscient role, forms of selective autophagy, relying on...

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PMID: 32918896
DOI: 10.1016/j.yexcr.2020.112276

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