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The Role of Autophagy and Autophagy Receptor NDP52 in Microbial Infections

16 Mar 2020

Abstract excerpt

Autophagy is a general protective mechanism for maintaining homeostasis in eukaryotic cells, regulating cellular metabolism, and promoting cell survival by degrading and recycling cellular components under stress conditions. The degradation pathway that is mediated by autophagy receptors is called selective autophagy, also named as xenophagy. Autophagy receptor NDP52 acts as a 'bridge' between autophagy and the...

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PMID: 32187990
DOI: 10.3390/ijms21062008

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