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Article

The effect of aging on VEGF/VEGFR2 signal pathway genes expression in rat liver sinusoidal endothelial cell.

Molecular and cellular biochemistry - 1 Jan 2021

Wang Wan-Li, Zheng Xing-Long, Li Qing-Shan, Liu Wen-Yan, Hu Liang-Shuo, Sha Huan-Chen, Guo Kun, Lv Yi, Wang Bo

Abstract excerpt

Liver sinusoidal endothelial cells (LSECs) play a key role in the initiation and neoangiogenesis of liver regeneration. We presume that the abnormity of the VEGF/VEGFR2 and its pathway gene Id1, Wnt2 and HGF expression in aged LSECs may be an important mechanism to affect liver regeneration of the elderly. LSECs from two different groups (adult and old) were isolated in a rodent model, and observed by SEM and...

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PMID: 32918705
DOI: 10.1007/s11010-020-03903-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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