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Article

Assessment of mismatch repair deficiency in ovarian cancer.

Journal of medical genetics - 1 Oct 2021

Crosbie Emma J, Ryan Neil A J, McVey Rhona J, Lalloo Fiona, Bowers Naomi, Green Kate, Woodward Emma R, Clancy Tara, Bolton James, Wallace Andrew J, McMahon Raymond F, Evans D Gareth

Abstract excerpt

BACKGROUND: Hereditary causes of ovarian cancer include Lynch syndrome, which is due to inherited pathogenic variants affecting one of the four mismatch repair genes involved in DNA repair. The aim of this study was to evaluate tumour mismatch repair deficiency and prevalence of Lynch syndrome in high-risk women referred to the Manchester Centre for Genomic Medicine with ovarian cancer over the past 20 years....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32917768
DOI: 10.1136/jmedgenet-2020-107270
PMCID: PMC8479746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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