Article
Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues
3 Sept 2020
Abstract excerpt
Night shift work increases risk of metabolic disorders, particularly obesity and insulin resistance. While the underlying mechanisms are unknown, evidence points to misalignment of peripheral oscillators causing metabolic disturbances. A pathway conveying such misalignment may involve exosome-based intercellular communication. Fourteen volunteers were assigned to a simulated day shift (DS) or night shift (NS)...
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