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Article

A normative modelling approach reveals age-atypical cortical thickness in a subgroup of males with autism spectrum disorder.

Communications biology - 4 Sept 2020

Bethlehem Richard A I, Seidlitz Jakob, Romero-Garcia Rafael, Trakoshis Stavros, Dumas Guillaume, Lombardo Michael V

Abstract excerpt

Understanding heterogeneity is an important goal on the path to precision medicine for autism spectrum disorders (ASD). We examined how cortical thickness (CT) in ASD can be parameterized as an individualized metric of atypicality relative to typically-developing (TD) age-related norms. Across a large sample (n = 870 per group) and wide age range (5-40 years), we applied normative modelling resulting in...

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Identifiers

PMID: 32887930
DOI: 10.1038/s42003-020-01212-9
PMCID: PMC7474067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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