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Article

Mapping the Heterogeneous Brain Structural Phenotype of Autism Spectrum Disorder Using the Normative Model.

Biological psychiatry - 1 Jun 2022

Shan Xiaolong, Uddin Lucina Q, Xiao Jinming, He Changchun, Ling Zihan, Li Lei, Huang Xinyue, Chen Huafu, Duan Xujun

Abstract excerpt

BACKGROUND: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by substantial clinical and biological heterogeneity. Quantitative and individualized metrics for delineating the heterogeneity of brain structure in ASD are still lacking. Likewise, the extent to which brain structural metrics of ASD deviate from typical development (TD) and whether deviations can be used for...

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PMID: 35367047
DOI: 10.1016/j.biopsych.2022.01.011

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