Article
Impact of MnSOD and GPx1 Genotype at Different Levels of Enteral Nutrition Exposure on Oxidative Stress and Mortality: A Post hoc Analysis From the FeDOx Trial.
JPEN. Journal of parenteral and enteral nutrition - 1 Feb 2021
McKeever Liam, Peterson Sarah J, Lateef Omar, Freels Sally, Diamond Alan M, Braunschweig Carol A
Abstract excerpt
BACKGROUND: Converting nutrition support to energy results in mitochondrial free radical production, possibly increasing oxidative stress. Highly prevalent single nucleotide variants (SNV) exist for the genes encoding antioxidant enzymes responsible for the detoxification of reactive oxygen species. Our objective was to explore the interaction between nutrition support and genetic SNV's for two anti-oxidant...
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