Modifiable Risk Factors for the Emergence of Ceftolozane-tazobactam Resistance

doi:10.1093/cid/ciaa1306

Article

Modifiable Risk Factors for the Emergence of Ceftolozane-tazobactam Resistance

1 Sept 2020

Abstract excerpt

BACKGROUND: Ceftolozane-tazobactam (TOL-TAZ) affords broad coverage against Pseudomonas aeruginosa. Regrettably, TOL-TAZ resistance has been reported. We sought to identify modifiable risk factors that may reduce the emergence of TOL-TAZ resistance. METHODS: Twenty-eight consecutive patients infected with carbapenem-resistant P. aeruginosa isolates susceptible to TOL-TAZ, treated with ≥72 hours of TOL-TAZ , and...

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