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Article

Implicit bias of encoded variables: frameworks for addressing structured bias in EHR-GWAS data.

Human molecular genetics - 30 Sept 2020

Dueñas Hillary R, Seah Carina, Johnson Jessica S, Huckins Laura M

Abstract excerpt

The 'discovery' stage of genome-wide association studies required amassing large, homogeneous cohorts. In order to attain clinically useful insights, we must now consider the presentation of disease within our clinics and, by extension, within our medical records. Large-scale use of electronic health record (EHR) data can help to understand phenotypes in a scalable manner, incorporating lifelong and whole-phenome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32879975
DOI: 10.1093/hmg/ddaa192
PMCID: PMC7530523

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