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Article

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy

2 Sept 2020

Abstract excerpt

-targeted therapeutics reduce TDP-43 pathology in vivo, and demonstrate that alterations in plasma NFL provide insight into the therapeutic efficacy of disease-modifying treatments.

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Identifiers

PMID: 32878979
DOI: 10.1126/scitranslmed.abb3774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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