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Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway

1 Sept 2020

Abstract excerpt

BACKGROUND/AIM: Despite advances in treatment modalities, the visual prognosis of retinoblastoma still remains unsatisfactory, underscoring the need to develop novel therapeutic approaches. MATERIALS AND METHODS: The effect on the growth of six human retinoblastoma cell lines and a normal human fibroblast cell line of CEP1347, a small-molecule kinase inhibitor originally developed for the treatment of Parkinson's...

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PMID: 32878784
DOI: 10.21873/anticanres.14499

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