Article
Cascade Screening for Familial Hypercholesterolemia in South Africa: The Wits FIND-FH Program.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2020
Raal Frederick J, Bahassi El Mustapha, Stevens Belinda, Turner Traci A, Stein Evan A
Abstract excerpt
OBJECTIVE: Due to gene founder effects, familial hypercholesterolemia (FH) has a prevalence of ≈1:80 in populations of Afrikaner ancestry and is a major contributor to premature atherosclerotic cardiovascular disease in South Africans of Jewish and Indian descent. No systematic program exists to identify these families. Furthermore, information regarding FH prevalence in Black Africans is sparse. The Wits FIND-FH...
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