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Article

A Genome-First Study of Familial Hypercholesterolemia Comparing African and European Ancestry Individuals.

Circulation - 16 Jun 2026

Winters Alexandra H, Kelly Melissa A, Syed Mohammad Ghouse, Bergquist Timothy, Berry Alexander S F, Mohammed Nuha, Cawley Dylan, Jones Laney K, Pejaver Vikas, Gidding Samuel S, Oetjens Matthew T

Abstract excerpt

BACKGROUND: Familial hypercholesterolemia (FH) is an inherited disorder characterized by lifelong elevated LDL-C (low-density lipoprotein cholesterol) and increased risk for premature myocardial infarction. FH research has focused on European populations and, consequently, estimates of global FH burden primarily reflect this ancestry, with limited data available from other groups. METHODS: We examined the...

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Identifiers

PMID: 42212376
DOI: 10.1161/CIRCULATIONAHA.126.080694
PMCID: PMC13225614

Genes

FH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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A Genome-First Study of Familial Hypercholesterolemia Comparing African and European Ancestry Individuals.PMID 42212376Read ↗

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