Article
Identification and characterization of a large source of primary mesenchymal stem cells tightly adhered to bone surfaces of human vertebral body marrow cavities.
Cytotherapy - 1 Nov 2020
Johnstone Brian H, Miller Hannah M, Beck Madelyn R, Gu Dongsheng, Thirumala Sreedhar, LaFontaine Michael, Brandacher Gerald, Woods Erik J
Abstract excerpt
BACKGROUND: Therapeutic allogeneic mesenchymal stromal cells (MSCs) are currently in clinical trials to evaluate their effectiveness in treating many different disease indications. Eventual commercialization for broad distribution will require further improvements in manufacturing processes to economically manufacture MSCs at scales sufficient to satisfy projected demands. A key contributor to the present high...
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