Article
Derivation of Multipotent Mesenchymal Stromal Cells from Ovine Bone Marrow.
Current protocols in stem cell biology - 28 Feb 2018
Vivas Daniel, Caminal Marta, Oliver-Vila Irene, Vives Joaquim
Abstract excerpt
In the field of orthopedics, translational research of novel therapeutic approaches involves the use of large animal models (such as sheep, goat, pig, dog, and horse) due to the similarities with humans in weight, size, joint structure, and bone/cartilage healing mechanisms. Particularly in the development of cell-based therapies, the lack of manageable immunocompromised preclinical large animal models prevents...
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