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Article

Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation.

Journal of bacteriology - 1 Jun 2008

Uehara Tsuyoshi, Park James T

Abstract excerpt

We have found a striking difference between the modes of action of amdinocillin (mecillinam) and compound A22, both of which inhibit cell elongation. This was made possible by employment of a new method using an Escherichia coli peptidoglycan (PG)-recycling mutant, lacking ampD, to analyze PG degradation during cell elongation and septation. Using this method, we have found that A22, which is known to prevent...

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Identifiers

PMID: 18390656
DOI: 10.1128/JB.00207-08
PMCID: PMC2395050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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