Article
Heterogeneity of Hereditary Hearing Loss in Iran: a Comprehensive Review.
Archives of Iranian medicine - 1 Oct 2016
Beheshtian Maryam, Babanejad Mojgan, Azaiez Hela, Bazazzadegan Niloofar, Kolbe Diana, Sloan-Heggen Christina, Arzhangi Sanaz, Booth Kevin, Mohseni Marzieh, Frees Kathy, Azizi Mohammad Hossein, Daneshi Ahmad, Farhadi Mohammad, Kahrizi Kimia, Smith Richard Jh, Najmabadi Hossein
Abstract excerpt
A significant contribution to the causes of hereditary hearing impairment comes from genetic factors. More than 120 genes and 160 loci have been identified to be involved in hearing impairment. Given that consanguine populations are more vulnerable to most inherited diseases, such as hereditary hearing loss (HHL), the genetic picture of HHL among the Iranian population, which consists of at least eight ethnic...
Topics
- Connexin 26
- Connexins
- Consanguinity
- Delivery of Health Care
- Genetic Testing
- Hearing Loss, Sensorineural
- Humans
- Iran
- Membrane Transport Proteins
- Mutation