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Article

Contribution of mast cells in irritant-induced airway epithelial barrier impairment in vitro.

Toxicology and industrial health - 1 Oct 2020

Van Den Broucke Sofie, Vanoirbeek Jeroen, Alfaro-Moreno Ernesto, Hoet Peter

Abstract excerpt

The airway epithelium is continuously exposed to environmental irritants, which can cause adverse effects such as irritant-induced asthma (IIA). Mast cells are located near airway epithelia and are able to respond to a variety of stimuli. We aimed to investigate whether mast cells influence the response of the epithelium upon irritant exposure. Two cell lines and three different seeding conditions, that is,...

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Identifiers

PMID: 32840447
DOI: 10.1177/0748233720948771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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