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Article

Epigenome-Wide Association Data Implicate Fetal/Maternal Adaptations Contributing to Clinical Outcomes in Preeclampsia

16 May 2019

Abstract excerpt

Aim: To investigate the changes of placental DNA methylome in preeclampsia (PE). Materials & methods: We performed an epigenome-wide association study in a Chinese cohort and six published datasets consisting of 335 samples in total. Results & conclusion: Numerous consistently hypomethylated probes were associated with early-onset PE in different populations, with 2125 reaching epigenome-wide significance. The...

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PMID: 31091979
DOI: 10.2217/epi-2019-0065

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