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Article

Liver disease in children with PiZZ alpha 1-antitrypsin deficiency.

Hepatology (Baltimore, Md.) - 1 Jan 2000

Ghishan F K, Greene H L

Abstract excerpt

We present our experience with 18 pediatric patients with alpha 1-antitrypsin deficiency of the PiZZ phenotype. Fifteen patients (83%) presented with neonatal cholestatic jaundice at a mean age of 2 +/- 0.6 months (+/- S.D.). The male:female ratio was 15:3, indicating a male predominance. All metabolic, infectious and obstructive causes of jaundice were ruled out by appropriate tests in the patients with neonatal...

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Identifiers

PMID: 3281887
DOI: 10.1002/hep.1840080220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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