Liver disease in children with PiZZ alpha 1-antitrypsin deficiency.

doi:10.1002/hep.1840080220

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Article

Liver disease in children with PiZZ alpha 1-antitrypsin deficiency.

Hepatology (Baltimore, Md.) - 1 Jan 2000

Ghishan F K, Greene H L

Abstract excerpt

We present our experience with 18 pediatric patients with alpha 1-antitrypsin deficiency of the PiZZ phenotype. Fifteen patients (83%) presented with neonatal cholestatic jaundice at a mean age of 2 +/- 0.6 months (+/- S.D.). The male:female ratio was 15:3, indicating a male predominance. All met...

Topics

Biopsy
Child
Child, Preschool
Cholestasis
Female
Humans
Infant
Liver
Liver Diseases
Liver Transplantation
Male
Phenotype
alpha 1-Antitrypsin Deficiency

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