alpha-1-Antitrypsin deficiency.

Article

alpha-1-Antitrypsin deficiency.

Hepatology (Baltimore, Md.) - 1 Jan 2000

Alagille D

Abstract excerpt

Liver disease related to alpha-1-antitrypsin deficiency occurs only in Pi ZZ homozygous children. Eleven per cent of Pi ZZ infants present with prolonged neonatal cholestasis. In our group, 25 of 45 Pi ZZ infants with prolonged neonatal cholestasis presented with later cirrhosis. Persistence of j...

Topics

Adolescent
Child
Child, Preschool
Cholestasis
Female
Follow-Up Studies
Humans
Infant
Liver Diseases
Male
Mortality
National Institutes of Health (U.S.)
Phenotype
United States
alpha 1-Antitrypsin Deficiency

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.