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Could high DNA stainability (HDS) be a valuable indicator of sperm nuclear integrity?

12 Aug 2020

Abstract excerpt

Abstract Background The Sperm Chromatin Structure Assay (SCSA®), in addition to identifying the DNA Fragmentation Index (DFI) also identifies High DNA satiability (HDS), supposed to reflect the nuclear compaction of spermatozoa. However, data on what exactly this parameter reveals, its relevance and usefulness are contradictory. In order to shed light on this situation, spermatozoa of a cohort (N = 397) of...

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PMID: 32817794
DOI: 10.1186/s12610-020-00110-8

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