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Article

Performance evaluation of an amplicon-based next-generation sequencing panel for BRCA1 and BRCA2 variant detection.

Journal of clinical laboratory analysis - 1 Dec 2020

Park Kuenyoul, Kim Min Kyu, Lee Taegeun, Hong Jinyoung, Kim Hyun-Ki, Ahn Sunyoung, Lee Young-Jae, Kim Jisun, Lee Shin-Wha, Lee Jong Won, Lee Woochang, Chun Sail, Son Byung Ho, Jung Kyung Hae, Kim Yong-Man, Min Won-Ki, Ahn Sei-Hyun

Abstract excerpt

BACKGROUND: As next-generation sequencing (NGS) technology matures, various amplicon-based NGS tests for BRCA1/2 genotyping have been introduced. This study was designed to evaluate an NGS test using a newly released amplicon-based panel, AmpliSeq for Illumina BRCA Panel (AmpliSeq panel), for detection of clinically significant BRCA variants, and to compare it to another amplicon-based NGS test confirmed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32812259
DOI: 10.1002/jcla.23524
PMCID: PMC7755770

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