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Article

Apelin enhances biological functions in lung cancer A549 cells by downregulating exosomal miR-15a-5p

13 Aug 2020

Abstract excerpt

Apelin acts as a tumor promoter in multiple malignant tumors; however, its regulatory mechanism remains unclear. Previous studies have indicated that exosomes are pivotal to mediating tumor progression and metastasis. This study examined whether apelin enhances proliferation and invasion ability of lung cancer cells via exosomal microRNA (miRNA). Lung cancer A549 cells overexpressing apelin and control vector...

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PMID: 32808032
DOI: 10.1093/carcin/bgaa089

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