Article
Evaluation of chromosomal abnormalities and copy number variations in late trimester pregnancy using cordocentesis.
Aging - 15 Aug 2020
Cai Meiying, Lin Na, Lin Yuan, Huang Hailong, Xu Liangpu
Abstract excerpt
Because the numbers of detected fetal abnormalities increase as gestation progresses, we evaluated the safety and efficacy of cordocentesis for single nucleotide polymorphism (SNP) analysis tests in 754 women during third trimester pregnancy. Conventional karyotyping was performed on all fetuses, and Affymetrix CytoScan HD was used for SNP-array testing. In addition to the 24 cases with chromosomal abnormalities...
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