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Article

Assessing the clinical application value of SNP-array in fetal central nervous system malformations.

Human genomics - 19 Nov 2025

Li Wei, Su Jiasun, Lu Weiliang, Tang Xianglian, Zhou Chaofan, Lan Yueyun, Wei Yuan, Huang Limei, Luo Jingrong, Ou Shan, Tan Shuyin, Wei Shengkai, Jiang Yaoyao, Su Jingyu, Wang Liang, Huang Minpan, Luo Jingsi, Huang Peng

Abstract excerpt

BACKGROUND: Single nucleotide polymorphism array (SNP-array) has been introduced for prenatal diagnosis. This study aims to evaluate the clinical utility of SNP-array in the prenatal central nervous system (CNS) malformations. METHODS: A retrospective study was conducted on 437 prenatal cases involving CNS malformations and other structural abnormalities detected by ultrasound. Samples were categorized into three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41258163
DOI: 10.1186/s40246-025-00843-5
PMCID: PMC12628932

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DLL1
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TGIF1

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