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Application of non-invasive prenatal testing for fetal chromosomal disorders in low-risk pregnancies: a follow-up study in central China

18 Jun 2025

Abstract excerpt

Objective: To evaluate the performance and screening value of noninvasive prenatal testing (NIPT) in low-risk pregnancies. Methods: A retrospective analysis was conducted on 60193 low-risk pregnancies over the last 5 years. Whole-genome sequencing of maternal plasma cell-free DNA was performed using next-generation sequencing. NIPT-positive results were confirmed using amniocentesis with karyotyping and/or copy...

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Share to Fetal and Pediatric Neurological Disorders
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

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PMID: 40606667
DOI: 10.3389/fgene.2025.1574775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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