Article
Integrated genetic and epigenetic analyses uncover MSI2 association with allergic inflammation.
The Journal of allergy and clinical immunology - 1 Apr 2021
Kim Kyung Won, Park Sang-Cheol, Cho Hyung-Ju, Jang Haerin, Park Jaehyun, Shim Hyo Sup, Kim Eun Gyul, Kim Mi Na, Hong Jung Yeon, Kim Yoon Hee, Lee Sanghun, Weiss Scott T, Kim Chang-Hoon, Won Sungho, Sohn Myung Hyun
Abstract excerpt
BACKGROUND: The relationship between allergic and eosinophilic inflammation, either systemic or local, in allergic diseases remains unclear. OBJECTIVE: We performed combined genome-wide association study (GWAS) and epigenome-wide (EWAS) for atopy and tissue eosinophilia to identify both genetic and epigenetic signatures between systemic and local allergic inflammation, and to capture global patterns of gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.