Article
Usefulness of Rapid Desensitization Therapy for Severe Rash Caused by Molecularly Targeted Drugs Used in the Treatment of Non-small-cell Lung Cancer.
Internal medicine (Tokyo, Japan) - 15 Dec 2020
Nagase Maki, Ohshima Nobuharu, Kawashima Masahiro, Ohgiya Masahiro, Ikeda Miki, Morio Yoshiteru, Tamura Atsuhisa
Abstract excerpt
Molecular-targeted drugs (MTDs), such as epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and anaplastic lymphoma kinase inhibitors, are used to treat non-small-cell lung cancer (NSCLC). The incidence of rash caused by EGFR-TKIs and discontinuation of MTDs because of rash are issues. Rapid desensitization therapy (RDT) was performed in five patients who developed severe rash after...
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