Article
Effective ultra-low doses of erlotinib in patients with EGFR sensitising mutation.
BMJ case reports - 23 Jul 2014
Szejniuk Weronika Maria, McCulloch Tine, Røe Oluf Dimitri
Abstract excerpt
We describe three cases of patients with advanced adenocarcinoma of the lung and epidermal growth factor receptor (EGFR) mutation treated with erlotinib 25 mg/day and 25 mg every second day, being equal to one-sixth and one-twelfth of the recommended dose. The mean age of our patients was above 70 with a WHO performance status 1 before and during the treatment. The reasons for erlotinib dose reduction were rash,...
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