Article
Diverse phenotypic measurements of wellbeing: Heritability, temporal stability and the variance explained by polygenic scores.
Genes, brain, and behavior - 1 Nov 2020
Jamshidi Javad, Williams Leanne M, Schofield Peter R, Park Haeme R P, Montalto Arthur, Chilver Miranda R, Bryant Richard A, Toma Claudio, Fullerton Janice M, Gatt Justine M
Abstract excerpt
Wellbeing, a key aspect of mental health, is moderately heritable with varying estimates reported from independent studies employing a variety of instruments. Recent genome-wide association studies (GWAS) have enabled the construction of polygenic scores (PGS) for wellbeing, providing the opportunity for direct comparisons of the variance explained by PGS for different instruments commonly employed in the field....
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