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Article

Quizartinib for the treatment of acute myeloid leukemia.

Expert opinion on pharmacotherapy - 1 Dec 2020

Garcia-Horton Alejandro, Yee Karen Wl

Abstract excerpt

INTRODUCTION: . Up to 30% of patients with acute myeloid leukemia (AML) have a mutation in the FLT3 receptor. Molecular targets have acquired a significant interest in the treatment of AML and are changing patient outcomes, including improvement of overall survival (OS) and remission rates. FLT3 inhibitors have obtained a central role in how we treat AML. AREAS COVERED: . This article reviews the mechanism of...

Topics

Antineoplastic Agents
Benzothiazoles
Clinical Trials, Phase III as Topic
Humans
Leukemia, Myeloid, Acute
Mutation
Phenylurea Compounds
Protein Kinase Inhibitors
Remission Induction
Treatment Outcome
fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32772726
DOI: 10.1080/14656566.2020.1801637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32772726-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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