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Article

Network-based modeling of drug effects on disease module in systemic sclerosis

7 Aug 2020

Abstract excerpt

The network-based proximity between drug targets and disease genes can provide novel insights regarding the repercussions, interplay, and repositioning of drugs in the context of disease. Current understanding and treatment for reversing of the fibrotic process is limited in systemic sclerosis (SSc). We have developed a network-based analysis for drug effects that takes into account the human interactome network,...

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PMID: 32770109
DOI: 10.1038/s41598-020-70280-y

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