Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Basic Science of Frailty-Biological Mechanisms of Age-Related Sarcopenia.

Anesthesia and analgesia - 1 Feb 2021

Csete Marie E

Abstract excerpt

Aging is associated with loss of function across organ systems, contributing to systemic frailty. Loss of skeletal muscle mass and function, in particular, is a major source of frailty in older adults, severely impacting quality of life. Some loss of muscle mass and strength with aging is inevitable, and sarcopenia, the severe loss of muscle mass with aging, is common. Sarcopenia is determined in part by genetics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Frail Elderly
Share to Frailty

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Health Status Indicators

Share to Life Style

Share to Muscle, Skeletal

Share to Sarcopenia

Source

Identifiers

PMID: 32769382
DOI: 10.1213/ANE.0000000000005096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Basic Science of Frailty-Biological Mechanisms of Age-Related Sarcopenia.PMID 32769382Read ↗

Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults.Semantic proximity Read ↗

Musculoskeletal frailty: a geriatric syndrome at the core of fracture occurrence in older age.Semantic proximity Read ↗

Aging of the Neuromuscular System: What Are the Causes of Age-Related Loss of Strength and Muscle Mass, and Can We Prevent Its Development and Progression?Semantic proximity Read ↗

Cellular and Molecular Basis of Age-Related SarcopeniaSemantic proximity Read ↗

Conceptual Models of Frailty: The Sarcopenia Phenotype.Semantic proximity Read ↗

Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and menSemantic proximity Read ↗

Experimental Models of Sarcopenia: Bridging Molecular Mechanism and Therapeutic Strategy.Semantic proximity Read ↗

Molecular and biological hallmarks of ageingSemantic proximity Read ↗

Sarcopenia of aging: Underlying cellular mechanisms and protection by calorie restrictionSemantic proximity Read ↗

Muscle function and fat content in relation to sarcopenia, obesity and frailty of old age--An overview.Semantic proximity Read ↗

Mouse sarcopenia model reveals sex- and age-specific differences in phenotypic and molecular characteristics.Semantic proximity Read ↗

Aging, disability and frailty.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.