Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TRIM31 enhances chemoresistance in glioblastoma through activation of the PI3K/Akt signaling pathway

21 May 2020

Abstract excerpt

Temozolomide (TMZ) resistance is a complication of treatment of glioma, and new strategies are urgently required to overcome chemoresistance in glioma cells. In the present study, it was demonstrated that tripartite motif‑containing 31 (TRIM31) was abnormally upregulated in glioma tissues and cell lines compared with normal samples. Furthermore, the role of TRIM31 was assessed by overexpressing and knocking down...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to interferon and immune responses
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32765650
DOI: 10.3892/etm.2020.8782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRIM31 enhances chemoresistance in glioblastoma through activation of the PI3K/Akt signaling pathwayPMID 32765650Read ↗

TRIM31 promotes proliferation, invasion and migration of glioma cells through Akt signaling pathwaySemantic proximity Read ↗

TRIM31: A molecule with a dual role in cancerSemantic proximity Read ↗

Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis PromoterSemantic proximity Read ↗

Interferon-γ inducible protein 30 promotes the epithelial-mesenchymal transition-like phenotype and chemoresistance by activating EGFR/AKT/GSK3β/β-catenin pathway in glioma.Semantic proximity Read ↗

<p>Knockdown Of TRIM31 Enhances Colorectal Cancer Radiosensitivity By Inducing DNA Damage And Activating Apoptosis</p>Semantic proximity Read ↗

TRIM31 is upregulated in hepatocellular carcinoma and promotes disease progression by inducing ubiquitination of TSC1–TSC2 complexSemantic proximity Read ↗

An investigation of the molecular characterization of the tripartite motif (TRIM) family and primary validation of TRIM31 in gastric cancerSemantic proximity Read ↗

Tripartite motif-containing 25 facilitates immunosuppression and inhibits apoptosis of glioma via activating NF-κBSemantic proximity Read ↗

TRIM8 downregulation in glioma affects cell proliferation and it is associated with patients survivalSemantic proximity Read ↗

Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathwaySemantic proximity Read ↗

TRIM59 knockdown inhibits cell proliferation by down-regulating the Wnt/β-catenin signaling pathway in neuroblastomaSemantic proximity Read ↗

Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stabilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.