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COVID-19: The Influence of ACE Genotype and ACE-I and ARBs on the Course of SARS-CoV-2 Infection in Elderly Patients.

Clinical interventions in aging - 1 Jan 2020

Sieńko Jerzy, Kotowski Maciej, Bogacz Anna, Lechowicz Kacper, Drożdżal Sylwester, Rosik Jakub, Sietnicki Marek, Sieńko Magdalena, Kotfis Katarzyna

Abstract excerpt

Since the beginning of 2020, the whole world has been struggling with the pandemic of Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus SARS-CoV-2. The SARS-CoV-2 infection depends on ACE2, TMPRSS2, and CD147, which are expressed on host cells. Several studies suggest that some single nucleotide polymorphisms (SNPs) of ACE2 might be a risk factor of COVID-19 infection. Genotypes affect ACE2...

Topics

Aged
Animals
Betacoronavirus
COVID-19
Comorbidity
Coronavirus Infections
Eye Diseases, Hereditary
Gene Frequency
Genotype
Humans
Pandemics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pneumonia, Viral

Retinal Diseases

SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 32764907
DOI: 10.2147/CIA.S261516
PMCID: PMC7382582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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