Article
Growth control of small-colony variants by genetic regulation of the hemin uptake system.
Infection and immunity - 1 Apr 2004
Roggenkamp Andreas, Hoffmann Harald, Hornef Mathias W
Abstract excerpt
Small-colony variants (SCVs) are slow-growing variants of human bacterial pathogens. They are associated with chronic persistent infections, and their biochemical identification and antimicrobial treatment are impaired by altered metabolic properties. To contribute to the understanding of SCV-mediated infections, we analyzed a clinical SCV isolate derived from a chronic prosthetic hip infection. A sequence...
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