Article
Protein O-mannosylation affects protein secretion, cell wall integrity and morphogenesis in Trichoderma reesei.
Fungal genetics and biology : FG & B - 1 Nov 2020
Zhao Guangya, Xu Yueqiang, Ouyang Haomiao, Luo Yuanming, Sun Shutao, Wang Zhongfu, Yang Jinghua, Jin Cheng
Abstract excerpt
Protein O-mannosyltransferases (PMTs) initiate O-mannosylation of proteins in the ER. Trichoderma reesei strains displayed a single representative of each PMT subfamily, Trpmt1, Trpmt2 and Trpmt4. In this work, two knockout strains ΔTrpmt1and ΔTrpmt4were obtained. Both mutants showed retarded growth, defective cell walls, reduced conidiation and decreased protein secretion. Additionally, the ΔTrpmt1strain...
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