Distinct early symptoms in neuropathologically proven frontotemporal lobar degeneration.

Abstract excerpt

OBJECTIVES: Frontotemporal lobar degeneration (FTLD) is associated with accumulation of neurodegeneration-related protein, such as tau, TAR DNA-binding protein 43 (TDP-43), or fused in sarcoma protein (FUS). There have been very few systematic studies of the early symptoms of clinical phenotypes: behavioral variant frontotemporal dementia (bvFTD), semantic variant primary progressive aphasia (svPPA). Clinical...

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• DNA-Binding Proteins
• Frontotemporal Dementia
• Frontotemporal Lobar Degeneration
• Phenotype
• RNA-Binding Protein FUS