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Clinical, Genetic, and Pathological Features of very Early Onset Frontotemporal Lobe Degeneration: A Systematic Review.

Current Alzheimer research - 1 Jan 2023

Chu Min, Wu Liyong, Liu Li, Nan Haitian, Jiang Deming, Wang Yihao, Rosa-Neto Pedro

Abstract excerpt

BACKGROUND: In most patients with frontotemporal lobe degeneration (FTLD), the degenerative process begins between the ages 45 and 65 years; onset younger than 45 years is relatively rare and considered very early onset FTLD (VEO-FTLD). OBJECTIVE: To delineate the clinical, genetic, and pathological features of VEO-FTLD. METHODS: A systematic literature review was carried out in PubMed and Embase from inception...

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PMID: 36573052
DOI: 10.2174/1567205020666221226122557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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