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Article

Intracellular and tissue specific expression of FTO protein in pig: changes with age, energy intake and metabolic status.

Scientific reports - 3 Aug 2020

Ferenc Karolina, Pilžys Tomaš, Garbicz Damian, Marcinkowski Michał, Skorobogatov Oleksandr, Dylewska Małgorzata, Gajewski Zdzisław, Grzesiuk Elżbieta, Zabielski Romuald

Abstract excerpt

Genome-wide association studies in the FTO gene have identified SNPs correlating with obesity and type 2 diabetes. In mice, lack of Fto function leads to intrauterine growth retardation and lean phenotype, whereas in human it is lethal. The aim of this study in a pig model was to determine the localization of the FTO protein in different tissues and cell compartments, in order to investigate potential targets of...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32747736
DOI: 10.1038/s41598-020-69856-5
PMCID: PMC7400765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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