Article
Temporal encoding of bacterial identity and traits in growth dynamics.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 2020
Zhang Carolyn, Song Wenchen, Ma Helena R, Peng Xiao, Anderson Deverick J, Fowler Vance G, Thaden Joshua T, Xiao Minfeng, You Lingchong
Abstract excerpt
In biology, it is often critical to determine the identity of an organism and phenotypic traits of interest. Whole-genome sequencing can be useful for this but has limited power for trait prediction. However, we can take advantage of the inherent information content of phenotypes to bypass these limitations. We demonstrate, in clinical and environmental bacterial isolates, that growth dynamics in standardized...
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