Article
Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis.
International journal of epidemiology - 1 Dec 2012
Staines-Urias Eleonora, Paez María C, Doyle Pat, Dudbridge Frank, Serrano Norma C, Ioannidis John P A, Keating Brendan J, Hingorani Aroon D, Casas Juan P
Abstract excerpt
BACKGROUND: Pre-eclampsia is thought to have a polygenic basis, but the identification of susceptibility genes and the quantification of associated risks have been elusive owing to lack of replication from published genetic association studies. OBJECTIVE: To perform a systematic review and meta-analysis of genetic association studies to evaluate the evidence for the associations of various candidate genes with...
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