Article
The distinct manifestation of young-onset amyotrophic lateral sclerosis in China.
Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Feb 2021
Lin Jianing, Chen Weineng, Huang Pian, Xie Youna, Zheng Minying, Yao Xiaoli
Abstract excerpt
OBJECTIVE: Young-onset amyotrophic lateral sclerosis (ALS) refers to ALS patients with initial symptoms earlier than 45 years, representing a novel disease pattern. We aim to summarize the clinical and genetic features of 102 young-onset ALS patients in China. Methods: Clinical information and blood samples were collected from all registered patients, and we performed next generation sequencing techniques in an...
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