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Article

Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies.

Investigative ophthalmology & visual science - 1 Jul 2020

Zhang Wenlin, Frausto Ricardo, Chung Doug D, Griffis Christopher G, Kao Liyo, Chen Angela, Azimov Rustam, Sampath Alapakkam P, Kurtz Ira, Aldave Anthony J

Abstract excerpt

Purpose: To elucidate the molecular events in solute carrier family 4 member 11 (SLC4A11)-deficient corneal endothelium that lead to the endothelial dysfunction that characterizes the dystrophies associated with SLC4A11 mutations, congenital hereditary endothelial dystrophy (CHED) and Fuchs endothelial corneal dystrophy 4. Methods: Comparative transcriptomic analysis (CTA) was performed in primary human corneal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Corneal Dystrophies, Hereditary

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Source

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Identifiers

PMID: 32721020
DOI: 10.1167/iovs.61.8.39
PMCID: PMC7425690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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