Comparison of Molecular Subtyping and Antimicrobial Resistance Detection Methods Used in a Large Multistate Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Linked to Pet Store Puppies.

doi:10.1128/JCM.00771-20

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Article

Comparison of Molecular Subtyping and Antimicrobial Resistance Detection Methods Used in a Large Multistate Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Linked to Pet Store Puppies.

Journal of clinical microbiology - 22 Sept 2020

Joseph Lavin A, Francois Watkins Louise K, Chen Jessica, Tagg Kaitlin A, Bennett Christy, Caidi Hayat, Folster Jason P, Laughlin Mark E, Koski Lia, Silver Rachel, Stevenson Lauren, Robertson Scott, Pruckler Janet, Nichols Megin, Pouseele Hannes, Carleton Heather A, Basler Colin, Friedman Cindy R, Geissler Aimee, Hise Kelley B, Aubert Rachael D

Abstract excerpt

Campylobacter jejuni is a leading cause of enteric bacterial illness in the United States. Traditional molecular subtyping methods, such as pulsed-field gel electrophoresis (PFGE) and 7-gene multilocus sequence typing (MLST), provided limited resolution to adequately identify C. jejuni outbreaks and separate out sporadic isolates during outbreak investigations. Whole-genome sequencing (WGS) has emerged as a...

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PMID: 32719029
DOI: 10.1128/JCM.00771-20
PMCID: PMC7512158

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