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Article

Exposure to Moderate Glycosuria Induces Virulence of Group B Streptococcus

17 Jul 2020

Abstract excerpt

To explore whether glycosuria induces virulence of uropathogens, in turn facilitating urinary tract infection (UTI), we exposed group B Streptococcus (GBS) strain 10/84 to human urine plain or with 300 mg/dL glucose (mimicking moderate glycosuria). Exposure to moderate glycosuria significantly augmented bacterial growth, kidney bacterial burden in a mouse model of ascending UTI, and virulence characteristics and...

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Share to Neonatal and Maternal Infections
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PMID: 32702082
DOI: 10.1093/infdis/jiaa443

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